Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
Genetic screens are a powerful tool to discover genes that are important in immune cell development and function.The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of china glaze beaches and toes zebrafish make this a powerful model system for this purpose.We used a Tol2-based gene-breaking transposon to